Therapeutic Drugs in Cancer
The first study examined the interaction between low doses of the multi-kinase inhibitor sorafenib and the histone deacetylase inhibitor vorinostat in colon cancer cells. Sorafenib and vorinostat synergized to kill HCT116 and SW480 cells. In SW480 cells, sorafenib+vorinostat toxicity correlated with...
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VCU Scholars Compass
2009
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| Online Access: | http://scholarscompass.vcu.edu/etd/1722 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=2721&context=etd |