Therapeutic Drugs in Cancer

The first study examined the interaction between low doses of the multi-kinase inhibitor sorafenib and the histone deacetylase inhibitor vorinostat in colon cancer cells. Sorafenib and vorinostat synergized to kill HCT116 and SW480 cells. In SW480 cells, sorafenib+vorinostat toxicity correlated with...

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Bibliographic Details
Main Author: Walker, Teneille
Format: Others
Published: VCU Scholars Compass 2009
Subjects:
Online Access:http://scholarscompass.vcu.edu/etd/1722
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=2721&context=etd

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