ROLES OF KRÜPPEL LIKE FACTORS KLF1, KLF2, AND KLF4 IN EMBRYONIC BETA-GLOBIN GENE EXPRESSION

Krüppel like factors (KLFs) are a family of 17 proteins whose main function is gene regulation by binding to DNA elements in the promoters of various genes. KLF transcription factors recognize CACCC-elements and act as activators or repressors of the gene expression. Among the 17 family members, KLF...

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Bibliographic Details
Main Author: Alhashem, Yousef
Format: Others
Published: VCU Scholars Compass 2009
Subjects:
Online Access:http://scholarscompass.vcu.edu/etd/1880
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=2879&context=etd