NEUTROPHIL PRODUCTS CONTROL THE EXPRESSION OF PROGESTERONE RECEPTORS AND MATRIX METALLOPROTEINASE-1 IN THE DECIDUAL AND MYOMETRIUM AND ARE POSSIBLE REGULATORS OF PREMATURE LABOR

Neutrophils infiltrate myometrium and decidual tissue prior to parturition. Activated neutrophils release reactive oxygen species (ROS) and tumor necrosis factor α (TNFα), which might increase expression of pro-labor genes such as matrix metalloproteinase-1 (MMP-1), progesterone receptor (PR) A/B ra...

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Bibliographic Details
Main Author: Solotskaya, Anna
Format: Others
Published: VCU Scholars Compass 2010
Subjects:
Online Access:http://scholarscompass.vcu.edu/etd/2112
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=3111&context=etd