Development and Implementation of a Tissue Specific MicroRNA Prediction Tool for Identifying Targets of the Tumor Suppressor microRNA 17-3p

A unique computational approach was undertaken to identify targets of miR-17-3p that impart an oncogenic potential to the cells of the prostate. Utilizing this approach, we identified insulin growth factor receptor 1 (IGF1R) as a potential target of miR-17-3p. IGF1R imparts an oncogenic approach to...

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Bibliographic Details
Main Author: Budd, William
Format: Others
Published: VCU Scholars Compass 2010
Subjects:
Online Access:http://scholarscompass.vcu.edu/etd/2116
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=3115&context=etd