CELL DEATH AND SUSTAINED SENESCENCE ARREST IN COLON CARCINOMA AND MELANOMA TUMOR CELLS IN RESPONSE TO THE NOVEL MICROTUBULE POISON, JG-03-14

Previous studies from this and other laboratories have shown that the novel microtubule poison, JG-03-14, which binds to the colchicine binding site of tubulin, has the capacity to promote both autophagy and apoptosis in breast tumor cells, as well as interfering with endothelial cell function and p...

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Bibliographic Details
Main Author: Biggers, Jonathan
Format: Others
Published: VCU Scholars Compass 2010
Subjects:
Online Access:http://scholarscompass.vcu.edu/etd/2206
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=3205&context=etd