ADAM10 exacerbation of allergic disease is potentially explained by its role in CD23 exosomal sorting.
CD23, the natural negative regulator of IgE, has been shown to be involved in asthma progression through its regulation of IgE. To investigate if its sheddase, ADAM10, is also involved in asthma progression, three mouse models were utilized; an IgE/mast cell dependent model, an IgE dependent, mast...
| Main Author: | |
|---|---|
| Format: | Others |
| Published: |
VCU Scholars Compass
2011
|
| Subjects: | |
| Online Access: | http://scholarscompass.vcu.edu/etd/2372 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=3371&context=etd |