SYNTHESIS AND CHARACTERIZATION OF DOXORUBICIN CARRYING CETUXIMAB-PAMAM DENDRIMER BIOCONJUGATES
A tumor targeted dendrimer based drug delivery system was designed and synthesized to carry chemotherapy drug doxorubicin. Polyamidoamine (PAMAM) dendrimer G4.5 was chosen as the underlying carrier. Anionic G4.5 is a good option for drug delivery as it consists of 128 surface groups, is less cytotox...
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| Format: | Others |
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VCU Scholars Compass
2012
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| Online Access: | http://scholarscompass.vcu.edu/etd/2788 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=3787&context=etd |