THE ANTINOCICEPTIVE EFFECTS OF ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR POSITIVE ALLOSTERIC MODULATORS IN DIFFERENT ANIMAL PAIN MODELS

The α7 nicotinic acetylcholine receptor (nAChR) subtype is abundantly expressed in the central nervous system (CNS) and in the periphery. Positive allosteric modulators (PAMs) of the α7 increase the response to an agonist and are divided into two types depending on whether they also decrease desensi...

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Bibliographic Details
Main Author: Freitas, Kelen
Format: Others
Published: VCU Scholars Compass 2012
Subjects:
Online Access:http://scholarscompass.vcu.edu/etd/2827
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=3826&context=etd