CELL DEATH AND GROWTH ARREST PATHWAYS MEDIATING THE ACTIONS OF STILBENE 5C IN HCT-116 COLON CANCER CELLS

Abstract The stilbene derivative, cis-3, 4’, 5-trimethoxy-3’-aminostilbene (stilbene 5c), is a potentially potent antitumor agent that acts via binding to the colchicine-binding pocket in microtubules. Earlier studies have shown that stilbene 5c induces cell death in ovarian cancer cells and leukem...

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Bibliographic Details
Main Author: Alotaibi, Moureq
Format: Others
Published: VCU Scholars Compass 2012
Subjects:
Online Access:http://scholarscompass.vcu.edu/etd/2851
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=3850&context=etd