PREDICTION OF HUMAN SYSTEMIC, BIOLOGICALLY RELEVANT PHARMACOKINETIC PROPERTIES BASED ON PHYSICOCHEMICAL PROPERTIES OF CALCIUM CHANNEL BLOCKERS
This research explored quantitative relationships (QSPKR) between different molecular descriptors and pertinent, systemic PK properties for 14 calcium channel blockers (CCB). Physicochemical properties (PC) such as molecular weight (MW), molar volume (MV), calculated logP (clogP), pKa, calculated lo...
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| Format: | Others |
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VCU Scholars Compass
2012
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| Online Access: | http://scholarscompass.vcu.edu/etd/2868 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=3867&context=etd |