Protein Kinase C Dependent Inhibition of Kir3.2 (GIRK2) Channel Activity and Its Molecular Determinants

Inwardly rectifying potassium (Kir) channels are critically important for regulating resting membrane potential in excitable cells, a job underscored by the severe pathophysiology associated with channel dysfunction. While all Kir channels require the activating lipid PIP2, many of these channels ha...

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Bibliographic Details
Main Author: Adney, Scott
Format: Others
Published: VCU Scholars Compass 2013
Subjects:
PKC
Online Access:http://scholarscompass.vcu.edu/etd/3214
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=4213&context=etd