Dissociable antidepressant-like and abuse-related effects of the noncompetitive NMDA receptor antagonists ketamine and MK-801 in rats.
The noncompetitive NMDA receptor antagonist ketamine produces rapid and sustained antidepressant effects in patients suffering from major depressive disorder. However, abuse liability is a concern. To further evaluate the relationship between antidepressant-like and abuse-related effects of NMDA rec...
| Main Author: | |
|---|---|
| Format: | Others |
| Published: |
VCU Scholars Compass
2014
|
| Subjects: | |
| Online Access: | http://scholarscompass.vcu.edu/etd/3326 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=4325&context=etd |