Redox Triggering of Podocyte NLRP3 Inflammasomes and Glomerular Injury in Hyperhomocysteinemia
Hyperhomocysteinemia (hHcys), an important pathogenic factor contributing to the progression of end-stage renal disease (ESRD), has been shown to activate NOD-like receptor protein 3 (NLRP3) inflammasomes and cause podocyte dysfunction and glomerular sclerosis. hHcys induces aggregation of the three...
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| Format: | Others |
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VCU Scholars Compass
2014
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| Online Access: | http://scholarscompass.vcu.edu/etd/3357 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=4356&context=etd |