The Effect of Damaged Bases on The End Joining of DNA Double Strand Break Ends
DNA double strand breaks (DSBs ) are extremely toxic to cells because they can lead to genomic rearrangements and even cell death. Two main pathways can repair DSBs: the homologous recombination repair (HRR) pathway and the non-homologous end-joining (NHEJ) pathway. NHEJ is the primary repair pathwa...
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| Format: | Others |
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VCU Scholars Compass
2014
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| Online Access: | http://scholarscompass.vcu.edu/etd/3516 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=4491&context=etd |