Biochemical and Structural studies of AAV-2 Rep68-AAVS1 complex assembly

Multiple DNA transactions are at the center of almost all processes regulating the AAV life cycle. A common feature shared by all transactions is the binding of the large AAV Rep proteins Rep78/Rep68 onto DNA sites harboring multiple GCTC repeats. AAV mediated site-specific integration is contingent...

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Bibliographic Details
Main Author: Bishop, Clayton
Format: Others
Published: VCU Scholars Compass 2014
Subjects:
Online Access:http://scholarscompass.vcu.edu/etd/3511
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=4496&context=etd