Regulation of Pancreatic α and β Cell Function by the Bile Acid Receptor TGR5
The discovery that bile acids act as endogenous ligands of the membrane receptor TGR5 and the nuclear receptor FXR increased their significance as regulators of cholesterol, glucose and energy metabolism. Activation of TGR5, expressed on enteroendocrine L cells, by bile acids caused secretion of GLP...
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| Format: | Others |
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VCU Scholars Compass
2014
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| Online Access: | http://scholarscompass.vcu.edu/etd/3591 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=4594&context=etd |