Investigations into the fluorescent covalent labeling of biomolecules utilizing rhodamine dyes, electrophilic leaving groups and mRNA display.
The discovery of a method by which proteins of interest can selectively be labeled with a probe of choice intracellularly is a longstanding goal in chemical biology research. Conventional labeling techniques have utilized large domain tags but despite the development of small labeling molecules ther...
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VCU Scholars Compass
2014
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| Online Access: | http://scholarscompass.vcu.edu/etd/3623 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=4650&context=etd |