TOLERANCE OF THYMINE GLYCOL AT THE BLUNT DNA DOUBLE STRAND BREAK FOR NONHOMOLOGUS END JOINING REPAIR AND INTERFERENCE BY BASE EXCISION REPAIR
Radiotherapy is the clinical application of the ionizing radiation to treat cancer. Ionizing radiation causes multiple modes of damage to the DNA damage such as SSBs, DSBs and modified bases such as thymine glycol. These lesions can exist as clusters in one or two helical turns of DNA. DNA double-s...
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Format: | Others |
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VCU Scholars Compass
2015
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Online Access: | http://scholarscompass.vcu.edu/etd/3921 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=4961&context=etd |