Investigation of Gain-of-Function Induced by Mutant p53
p53 is mutated in 50% of all human cancers, and up to 70% of lung cancer. Mutant p53 is usually expressed at elevated levels in cancer cells and has been correlated with a poor prognosis. Cancer cells that express mutant p53 show an increase in oncogenic phenotypes including an increase in growth...
Main Author: | Vaughan, Catherine |
---|---|
Format: | Others |
Published: |
VCU Scholars Compass
2015
|
Subjects: | |
Online Access: | http://scholarscompass.vcu.edu/etd/3965 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=5001&context=etd |
Similar Items
-
Mathematical Models of Some Signaling Pathways Regulating Cell Survival and Death
by: Zhang, Tongli
Published: (2014) -
Characterization of the Anti-Obesity and Anti-Adipogenic Effects of the Limonoid Prieurianin
by: Saunders, Rudel Anton
Published: (2010) -
Effect of implant surface roughness on the NFkB signalling pathway in macrophages
by: Ali, Tarek Adel
Published: (2008) -
Effect of implant surface roughness on the NFkB signalling pathway in macrophages
by: Ali, Tarek Adel
Published: (2008) -
Effect of implant surface roughness on the NFkB signalling pathway in macrophages
by: Ali, Tarek Adel
Published: (2008)