INTRODUCING NOVEL COMBINATORIAL TARGETED THERAPIES IN MULTIPLE TYPES OF CANCER
The cancers of liver, colon and breast are amongst the top five most prevalent and most fatal worldwide. As the Raf/MEK/ERK pathway is frequently deregulated in hepatocellular carcinoma (HCC), sorafenib, a Raf kinase inhibitor, became the first systemic therapy approved for the treatment of patients...
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VCU Scholars Compass
2016
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| Online Access: | http://scholarscompass.vcu.edu/etd/4088 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=5141&context=etd |