Pharmacological Inhibition of Cyclophilin Ameliorates Experimental Allergic Encephalomyelitis
A subset of cyclophilins have been implicated in mechanisms of neuroinflammation and neurodegeneration that contributes to the pathogenesis of Multiple Sclerosis. Mitochondrial dysfunction leading to mitochondrial permeability transition plays a pivotal role in axonal damage and disease progression...
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VCU Scholars Compass
2016
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| Online Access: | http://scholarscompass.vcu.edu/etd/4294 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=5295&context=etd |