A MECHANISTIC STUDY OF AN iPSC MODEL FOR LEIGH’S DISEASE CAUSED BY MtDNA MUTATAION (8993 T>G)

Mitochondrial diseases encompass a broad range of devastating disorders that typically affect tissues with high-energy requirements. These disorders have been difficult to diagnose and research because of the complexity of mitochondrial genetics, and the large variability seen among patient populati...

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Bibliographic Details
Main Author: Galdun, John P
Format: Others
Published: VCU Scholars Compass 2016
Subjects:
Online Access:http://scholarscompass.vcu.edu/etd/4411
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=5445&context=etd