Allosteric Effects of G-Protein Coupled Receptor Heteromerization: Relevance to Psychosis
G-protein coupled receptors (GPCRs) implicated in disease are the predominant pharmaceutical targets. Growing evidence suggests that GPCRs form homo- and heteromeric complexes, resulting in allosteric functional changes. Ligands targeting one receptor can alter the function of the other receptor or...
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VCU Scholars Compass
2016
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| Online Access: | http://scholarscompass.vcu.edu/etd/4457 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=5508&context=etd |