CHARACTERIZATION OF THE ROLE OF INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 7 (IGFBP7) USING A GENETIC KNOCKOUT MOUSE MODEL

CHARACTERIZATION OF THE ROLE OF INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 7 (IGFBP7) USING A GENETIC KNOCKOUT MOUSE MODEL

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In the US, the incidence and mortality rates of hepatocellular carcinoma (HCC) are alarmingly increasing since no effective therapy is available for the advanced disease. Activation of IGF signaling is a major oncogenic event in diverse cancers, including HCC. Insulin-like growth factor binding prot...

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Bibliographic Details
Main Author: Akiel, Maaged A
Format: Others
Published: VCU Scholars Compass 2017
Subjects:
IGF signaling
antigen presentation
tumor suppression
inflammation
mouse model
Medical Cell Biology
Medical Genetics
Medical Pathology
Medicine and Health Sciences
Translational Medical Research
Online Access:http://scholarscompass.vcu.edu/etd/4934
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=6019&context=etd

Internet

http://scholarscompass.vcu.edu/etd/4934
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=6019&context=etd

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