Gastrointestinal Microbiota Modulate Antinociceptive Tolerance Development in Mice with Chronic Morphine Exposure

In October 2017, the United States government declared a state of public health emergency in response to the burgeoning prescription opioid epidemic. Opioid analgesics are the gold standard of therapy for moderate to severe pain, but their clinical utility is greatly limited by analgesic tolerance –...

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Bibliographic Details
Main Author: Mischel, Ryan A
Format: Others
Published: VCU Scholars Compass 2018
Subjects:
Online Access:https://scholarscompass.vcu.edu/etd/5283
https://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=6361&context=etd