The Role of ADAM10 and ADAM17 in Humoral and Type 2 Immunity
The proper regulation of inducible costimulator (ICOS) and its ligand (ICOSL) have been shown to be essential for maintaining immune homeostasis. Loss of either protein results in defective humoral immunity, and overexpression of ICOS results in aberrant antibody production resembling lupus. How ICO...
| Main Author: | |
|---|---|
| Format: | Others |
| Published: |
VCU Scholars Compass
2018
|
| Subjects: | |
| Online Access: | https://scholarscompass.vcu.edu/etd/5680 https://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=6767&context=etd |