Development of Bivalent Ligands Targeting the Putative Mu Opioid Receptor and Chemokine Receptor CXCR4 Heterodimer
Human immunodeficiency virus (HIV) and opioid abuse have been described as synergistic epidemics. Pharmacologically, it has been found that opioids have the capacity to enhance HIV infection and replication. Research has shown that activation of the mu-opioid receptor (MOR) elevates the expression o...
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VCU Scholars Compass
2019
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| Online Access: | https://scholarscompass.vcu.edu/etd/5754 https://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=6866&context=etd |