Connecting the Dots: Investigating the Effects of Trans-Synaptic Tau Transmission in the Hippocampus

Connecting the Dots: Investigating the Effects of Trans-Synaptic Tau Transmission in the Hippocampus

Tauopathy, which results from the oligomerization of misfolded tau protein in neurons, is a feature present in a number of neurodegenerative diseases and a hallmark of Alzheimer’s Disease (AD). Tau is an important phosphoprotein that regulates the assembly of microtubules, but tauopathy can occur wh...

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Bibliographic Details
Main Author: Bamisile, Michael
Format: Others
Published: VCU Scholars Compass 2019
Subjects:
Alzheimer's Disease
neurodegeneration
trans-synaptic tau transmission
tau
hippocampus
entorhinal cortex
inhibitory interneurons
principal cells
VGAT
calretinin
Medicine and Health Sciences
Online Access:https://scholarscompass.vcu.edu/etd/5831
https://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=6867&context=etd

Internet

https://scholarscompass.vcu.edu/etd/5831
https://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=6867&context=etd

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