A computational study of somatostatin subtype-4 receptor agonist binding

The somatostatin subtype-4 receptor (sst4) is highly expressed in neocortical and hippocampal areas, which are affected by amyloid beta accumulation. Sst4 agonists enhance downstream activity of amyloid beta peptide catabolism through neprilysin and may slow the progression of Alzheimer’s disease (A...

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Bibliographic Details
Main Authors: Kontoyianni, M. (Author), Slater, O. (Author)
Format: Article
Language:English
Published: Springer Nature 2022
Subjects:
Online Access:View Fulltext in Publisher