A computational study of somatostatin subtype-4 receptor agonist binding
The somatostatin subtype-4 receptor (sst4) is highly expressed in neocortical and hippocampal areas, which are affected by amyloid beta accumulation. Sst4 agonists enhance downstream activity of amyloid beta peptide catabolism through neprilysin and may slow the progression of Alzheimer’s disease (A...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |