Reactive oxygen species (ROS)-responsive size-reducible nanoassemblies for deeper atherosclerotic plaque penetration and enhanced macrophage-targeted drug delivery

Reactive oxygen species (ROS)-responsive size-reducible nanoassemblies for deeper atherosclerotic plaque penetration and enhanced macrophage-targeted drug delivery

Nanoparticle-based therapeutics represent potential strategies for treating atherosclerosis; however, the complex plaque microenvironment poses a barrier for nanoparticles to target the dysfunctional cells. Here, we report reactive oxygen species (ROS)-responsive and size-reducible nanoassemblies, f...

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Bibliographic Details
Main Authors: He, H. (Author), He, J. (Author), Liu, J. (Author), Xu, F. (Author), Yang, H. (Author), Zhang, Q. (Author), Zhang, W. (Author), Zhao, Y. (Author), Zhou, X. (Author), Zou, J. (Author)
Format: Article
Language:English
Published: KeAi Communications Co. 2023
Subjects:
Atherosclerosis
Macrophage
Reactive oxygen species
Recombinant high-density lipoprotein
Size-reducible nanoassemblies
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