Topical instillation of cell-penetrating peptide-conjugated melphalan blocks metastases of retinoblastoma

Retinoblastoma is the most common primary intraocular malignancy in infancy with a metastases-related death risk. However, a safe and convenient treatment without enucleation is still an unmet clinical need. In this work, a cell-penetrating peptide, 89WP, was conjugated with melphalan (89WP-Mel), wh...

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Bibliographic Details
Main Authors: Fan, X. (Author), Hu, Y. (Author), Jiang, K. (Author), Liu, Y. (Author), Lu, W. (Author), Wei, G. (Author), Yao, S. (Author), Zhan, C. (Author)
Format: Article
Language:English
Published: Elsevier Ltd 2022
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