Topical instillation of cell-penetrating peptide-conjugated melphalan blocks metastases of retinoblastoma
Retinoblastoma is the most common primary intraocular malignancy in infancy with a metastases-related death risk. However, a safe and convenient treatment without enucleation is still an unmet clinical need. In this work, a cell-penetrating peptide, 89WP, was conjugated with melphalan (89WP-Mel), wh...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier Ltd
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |