Magnetic Nanoparticle-Mediated Orientation of Collagen Hydrogels for Engineering of Tendon-Mimetic Constructs

Magnetic Nanoparticle-Mediated Orientation of Collagen Hydrogels for Engineering of Tendon-Mimetic Constructs

Despite the high incidence of tendon injuries worldwide, an optimal treatment strategy has yet to be defined. A key challenge for tendon repair is the alignment of the repaired matrix into orientations which provide maximal mechanical strength. Using oriented implants for tissue growth combined with...

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Bibliographic Details
Main Authors: Broomhall, T.J (Author), El Haj, A.J (Author), Lamont, H.C (Author), Righelli, L. (Author), Wright, A.L (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2022
Subjects:
alignment
biomaterials
collagen
Collagen
Collagen I
Fluorescence microscopy
Gels
High incidence
Human adipose stem cells
hydrogels
Hydrogels
Magnetic fields
Magnetic-field
magnets
matrix
Matrix algebra
Mimetics
Network architecture
Optimal treatment
Scaffolds (biology)
Stem cells
Tendon injuries
Tendon repairs
tendons
Tendons
tissue engineering
Tissues engineerings
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