Biomimetic Redox-Responsive Mesoporous Organosilica Nanoparticles Enhance Cisplatin-Based Chemotherapy

Biomimetic Redox-Responsive Mesoporous Organosilica Nanoparticles Enhance Cisplatin-Based Chemotherapy

Cisplatin-based chemotherapy is dominated in several cancers; however, insufficient therapeutic outcomes and systemic toxicity hamper their clinical applications. Controlled release of cisplatin and reducing inactivation remains an urgent challenge to overcome. Herein, diselenide-bridged mesoporous...

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Bibliographic Details
Main Authors: Cao, L. (Author), Chang, Z. (Author), Chen, F. (Author), Chen, M. (Author), Dong, W.-F (Author), Ge, M. (Author), Li, L. (Author), Mei, Q. (Author), Peng, J. (Author), Wang, Y. (Author), Zhang, F. (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2022
Subjects:
biomimetic nanocarrier
Biomimetic nanocarrier
Biomimetics
Cardiovascular system
Cells
Chemotherapy
cisplatin
Cisplatin
Cis-platin
Controlled release
Cytology
degradation
Diseases
glutathione depletion
Glutathione depletion
Gluthathione
Mesoporous materials
Mesoporous organosilicas
mesoporous silica nanoparticles
Mesoporous silica nanoparticles
Nanocarriers
Redox-responsive
Selenium compounds
Silica nanoparticles
Toxicity
Tumors
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