Risk of Opioid Overdose Associated with Concomitant Use of Oxycodone and Selective Serotonin Reuptake Inhibitors

Importance: Some selective serotonin reuptake inhibitors (SSRIs) inhibit the enzymes responsible for the metabolism of oxycodone, a potent prescription opioid. The clinical consequences of this interaction on the risk of opioid overdose have not been elucidated. Objective: To compare opioid overdose...

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Bibliographic Details
Main Authors: Bykov, K. (Author), Gagne, J.J (Author), Yoshida, K. (Author), Yunusa, I. (Author)
Format: Article
Language:English
Published: American Medical Association 2022
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Online Access:View Fulltext in Publisher