Prolonged exposure to simulated microgravity promotes stemness impairing morphological, metabolic and migratory profile of pancreatic cancer cells: a comprehensive proteomic, lipidomic and transcriptomic analysis

Prolonged exposure to simulated microgravity promotes stemness impairing morphological, metabolic and migratory profile of pancreatic cancer cells: a comprehensive proteomic, lipidomic and transcriptomic analysis

Background: The impact of the absence of gravity on cancer cells is of great interest, especially today that space is more accessible than ever. Despite advances, few and contradictory data are available mainly due to different setup, experimental design and time point analyzed. Methods: Exploiting...

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Bibliographic Details
Main Authors: Andreoli, F. (Author), Barberis, E. (Author), Bonetto, V. (Author), Donadelli, M. (Author), Fiore, A. (Author), Manfredi, M. (Author), Marengo, E. (Author), Masetto, F. (Author), Masini, M.A (Author), Pastò, A. (Author), Robotti, E. (Author), Sica, A. (Author), Tavella, S. (Author), Timo, S. (Author), Vanella, V.V (Author)
Format: Article
Language:English
Published: Springer Science and Business Media Deutschland GmbH 2022
Subjects:
Cancer stem cells
Lipidomic
Metabolism
Microgravity
Proteomic
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