Magnetic Resonance Imaging Characteristics of Molecular Subgroups in Pediatric H3 K27M Mutant Diffuse Midline Glioma

Magnetic Resonance Imaging Characteristics of Molecular Subgroups in Pediatric H3 K27M Mutant Diffuse Midline Glioma

Purpose: Recent research identified histone H3 K27M mutations to be associated with a dismal prognosis in pediatric diffuse midline glioma (pDMG); however, data on detailed MRI characteristics with respect to H3 K27 mutation status and molecular subgroups (H3.1 and H3.3 K27M mutations) are limited....

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Bibliographic Details
Main Authors: Bison, B. (Author), Gielen, G.H (Author), Hoffmann, M. (Author), Hohm, A. (Author), Karremann, M. (Author), Kramm, C.M (Author), Nowak, J. (Author), Pham, M. (Author), Pietsch, T. (Author), Stock, A. (Author), Vandergrift, L.A (Author), Warmuth-Metz, M. (Author)
Format: Article
Language:English
Published: Springer Science and Business Media Deutschland GmbH 2022
Subjects:
adolescent
Adolescent
Brain Neoplasms
brain tumor
child
Child
diagnostic imaging
genetics
glioma
Glioma
histone
Histones
human
Humans
Imaging
Magnetic Resonance Imaging
Molecular subgroups
nuclear magnetic resonance imaging
pathology
Pediatric brain tumors
Radiogenomics
Retrospective Studies
retrospective study
WHO classification
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