Gene Set Enrichment Analsyes Identiify Pathways Involved in Genetic Risk for Diabetic Retinopathy: GSEA Identify Pathways Involved in Genetic Risk for DR

Gene Set Enrichment Analsyes Identiify Pathways Involved in Genetic Risk for Diabetic Retinopathy: GSEA Identify Pathways Involved in Genetic Risk for DR

To identify functionally related genes associated with diabetic retinopathy (DR) risk using gene set enrichment analyses applied to genome-wide association study meta-analyses. Methods: We analyzed DR GWAS meta-analyses performed on 3246 Europeans and 2611 African Americans with type 2 diabetes. Gen...

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Bibliographic Details
Main Authors: Adler, S.G (Author), Bowden, D.W (Author), Burdon, K.P (Author), Chen, C.J (Author), Chew, E.Y (Author), Cotch, M.F (Author), Craig, J.E (Author), Freedman, B.I (Author), Igo Jr, R.P (Author), Iyengar, S.K (Author), Jensen, R.A (Author), Klein, B.E.K (Author), Kuo, J.Z (Author), Li, A. (Author), Li, X. (Author), Mitchell, P. (Author), Ng, M.C.Y (Author), Penman, A. (Author), Pollack, S. (Author), Rotter, J.I (Author), Rouhana, J.M (Author), Segrè, A.V (Author), Smith, A.V (Author), Sobrin, L. (Author), Stanwyck, L. (Author), Susarla, G. (Author), Taylor, K.D (Author), Wang, J.J (Author), Wong, T.Y (Author), Yaspan, B. (Author)
Format: Article
Language:English
Published: Elsevier Inc. 2022
Subjects:
apoptosis
Article
biosynthesis
Diabetes Mellitus, Type 2
diabetic retinopathy
Diabetic Retinopathy
gamma interferon
genetic association
genetic risk
genetics
genome-wide association study
Genome-Wide Association Study
human
Humans
meta analysis
nerve cell degeneration
non insulin dependent diabetes mellitus
pathophysiology
Polymorphism, Single Nucleotide
predictive value
protein protein interaction
retina ganglion cell
risk factor
Risk Factors
single nucleotide polymorphism
systematic review
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