The hepatocyte insulin receptor is required to program the liver clock and rhythmic gene expression

The hepatocyte insulin receptor is required to program the liver clock and rhythmic gene expression

Liver physiology is circadian and sensitive to feeding and insulin. Food intake regulates insulin secretion and is a dominant signal for the liver clock. However, how much insulin contributes to the effect of feeding on the liver clock and rhythmic gene expression remains to be investigated. Insulin...

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Bibliographic Details
Main Authors: Benani, A. (Author), Burnol, A.-F (Author), Dopavogui, L. (Author), Duez, H. (Author), Ellero-Simatos, S. (Author), Fougerat, A. (Author), Fougeray, T. (Author), Gamet-Payrastre, L. (Author), Gigot, V. (Author), Gourdy, P. (Author), Guillou, H. (Author), Haas, J.T (Author), Huillet, M. (Author), Lasserre, F. (Author), Lippi, Y. (Author), Loiseau, N. (Author), Montagner, A. (Author), Naylies, C. (Author), Nédélec, E. (Author), Polizzi, A. (Author), Postic, C. (Author), Régnier, M. (Author), Salvi, J. (Author), Smati, S. (Author), Smith, L. (Author), Sommer, C. (Author), Tramunt, B. (Author), Wahli, W. (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2022
Subjects:
circadian
CLOCK
CP: Metabolism
CP: Molecular biology
hepatocyte
insulin
insulin receptor
liver
metabolism
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