Global post-translational modification profiling of HIV-1-infected cells reveals mechanisms of host cellular pathway remodeling

Global post-translational modification profiling of HIV-1-infected cells reveals mechanisms of host cellular pathway remodeling

Viruses must effectively remodel host cellular pathways to replicate and evade immune defenses, and they must do so with limited genomic coding capacity. Targeting post-translational modification (PTM) pathways provides a mechanism by which viruses can broadly and rapidly transform a hostile host en...

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Bibliographic Details
Main Authors: Adhikary, P. (Author), Beltrao, P. (Author), Cox, J.S (Author), Crosby, D.C (Author), Frankel, A.D (Author), Fregoso, O.I (Author), Hultquist, J.F (Author), Hüttenhain, R. (Author), Johnson, J.R (Author), Johnson, T.L (Author), Krogan, N.J (Author), Kurland, A.P (Author), Li, D. (Author), Marlett, J. (Author), Marson, A. (Author), Newton, B.W (Author), Shales, M. (Author), Simon, V.A (Author), Swann, J. (Author), Verschueren, E. (Author), Young, J.A.T (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2022
Subjects:
b56
CP: Microbiology
CP: Molecular biology
histone h1
HIV-1
phosphorylation
pp2a
proteomics
systems biology
ubiquitination
vif
vpr
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