Post-Transplantation Cyclophosphamide Is Associated with an Increase in Non-Cytomegalovirus Herpesvirus Infections in Patients with Acute Leukemia and Myelodysplastic Syndrome

Post-Transplantation Cyclophosphamide Is Associated with an Increase in Non-Cytomegalovirus Herpesvirus Infections in Patients with Acute Leukemia and Myelodysplastic Syndrome

The use of post-transplantation cyclophosphamide (PTCy) for graft-versus-host disease (GVHD) prophylaxis in recipients of haploidentical and fully matched transplantations is on the increase. Published studies have reported an increased incidence of cytomegalovirus (CMV) infection with the use of PT...

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Main Authors: Abid, M.B (Author), Badawy, S.M (Author), Beitinjaneh, A. (Author), Chen, M. (Author), Dandoy, C.E (Author), De Oliveir, S. (Author), Friend, B.D (Author), Ganguly, S. (Author), Goldsmith, S.R (Author), Hematti, P. (Author), Hill, J.A (Author), Kanakry, C.G (Author), Kanakry, J.A (Author), Kharfan-Dabaja, M.A (Author), Kim, S. (Author), Komanduri, K.V (Author), Lazarus, H.M (Author), Maziarz, R.T (Author), Mulroney, C.M (Author), Patel, S.S (Author), Perales, M.-A (Author), Politikos, I. (Author), Riches, M. (Author), Romee, R. (Author), Singh, A. (Author), Taplitz, R. (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2022
Subjects:
acute graft versus host disease
acute leukemia
acute lymphoblastic leukemia
acute myeloid leukemia
adolescent
adult
age
aged
Article
calcineurin inhibitor
Charlson Comorbidity Index
child
chronic graft versus host disease
cohort analysis
controlled study
cyclophosphamide
Cyclophosphamide
cytomegalovirus infection
Cytomegalovirus Infections
disease free survival
Epstein-Barr virus
female
graft versus host reaction
granulocyte colony stimulating factor
Haploidentical
haploidentical transplantation
hematopoietic stem cell transplantation
herpes virus infection
Herpesviridae
HHV-6
human
human tissue
Humans
infection risk
Leukemia, Myeloid, Acute
major clinical study
male
matched sibling donor
methotrexate
mortality
multicenter study
mycophenolate mofetil
myelodysplastic syndrome
Myelodysplastic Syndromes
Non-CMV herpesvirus
observational study
peripheral blood stem cell
posttransplant lymphoproliferative disease
Post-transplantation cyclophosphamide
Prospective Studies
prospective study
retrospective study
sex difference
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