Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function

Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function

Objective: Fibrotic organ responses have recently been identified as long-term complications in diabetes. Indeed, insulin resistance and aberrant hepatic lipid accumulation represent driving features of progressive non-alcoholic fatty liver disease (NAFLD), ranging from simple steatosis and non-alco...

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Main Authors: Blüher, M. (Author), Chivukula, P. (Author), De Angelis Rigotti, F. (Author), Deligiannis, I.K (Author), Ekim-Üstünel, B. (Author), Fischer, A. (Author), Hackert, T. (Author), Herzig, S. (Author), Karmali, P. (Author), Kwon, Y. (Author), Limphong, P. (Author), Maida, A. (Author), Martinez-Jimenez, C.P (Author), Mhamane, A. (Author), Morgenstern, J. (Author), Mukthavaram, R. (Author), Nawroth, P. (Author), Payne, J. (Author), Poth, T. (Author), Roden, M. (Author), Rodriguez-Vita, J. (Author), Sakurai, M. (Author), Sekar, R. (Author), Szendrödi, J. (Author), Tachikawa, K. (Author), Troullinaki, M. (Author), Volk, N. (Author), Weber, P. (Author), Wieder, A. (Author), Wiedmann, L. (Author), Wolff, G. (Author), Yin, K. (Author), Zeigerer, A. (Author)
Format: Article
Language:English
Published: Elsevier GmbH 2022
Subjects:
Fibrosis
Hepatocyte-specific
NAFLD
NASH
TSC22D4
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