Multiscale structural mapping of Alzheimer's disease neurodegeneration

Multiscale structural mapping of Alzheimer's disease neurodegeneration

The recently described biological framework of Alzheimer's disease (AD) emphasizes three types of pathology to characterize this disorder, referred to as the ‘amyloid/tau/neurodegeneration’ (A-T-N) status. The ‘neurodegenerative’ component is typically defined by atrophy measures derived from s...

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Bibliographic Details
Main Authors: Dickerson, B.C (Author), Jang, I. (Author), Li, B. (Author), Riphagen, J.M (Author), Salat, D.H (Author)
Format: Article
Language:English
Published: Elsevier Inc. 2022
Subjects:
aged
Aged
Alzheimer disease
Alzheimer Disease
Alzheimer's disease
Article
atrophy
Atrophy
Biomarker
brain mapping
brain size
brain ventricle
cerebrospinal fluid
cognitive defect
Cognitive Dysfunction
controlled study
Cortical thickness
cortical thickness (brain)
dementia
diagnostic accuracy
diagnostic test accuracy study
entorhinal cortex
false positive result
female
fluorodeoxyglucose f 18
fusiform gyrus
gray matter
Gray matter to white matter contrast
hippocampus
Hippocampus
human
human tissue
Humans
machine learning
Magnetic Resonance Imaging
major clinical study
male
middle temporal gyrus
mild cognitive impairment
Mild cognitive impairment
Mini Mental State Examination
Montreal cognitive assessment
Multiscale mapping
neuroimaging
nuclear magnetic resonance imaging
pathology
procedures
Rey auditory verbal learning test
sensitivity and specificity
standardized uptake value ratio
white matter
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