Establishment of a pancreatic cancer animal model using the pancreas-targeted hydrodynamic gene delivery method

Establishment of a pancreatic cancer animal model using the pancreas-targeted hydrodynamic gene delivery method

This research developed an easy-to-use, reproducible pancreatic cancer animal model utilizing pancreas-targeted hydrodynamic gene delivery to deliver human pancreatic cancer-related genes to the pancreas of wild-type rats. KRASG12D-induced pancreatic intraepithelial neoplasia lesions showed malignan...

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Bibliographic Details
Main Authors: Abe, H. (Author), Hayashi, K. (Author), Ikarashi, S. (Author), Kamimura, K. (Author), Kimura, A. (Author), Morita, S. (Author), Oda, C. (Author), Ogawa, K. (Author), Owaki, T. (Author), Shibata, O. (Author), Tanaka, Y. (Author), Terai, S. (Author), Yokoo, T. (Author)
Format: Article
Language:English
Published: Cell Press 2022
Subjects:
animal model
delivery strategies
gene delivery
hydrodynamic gene delivery
oncogene
pancreatic cancer
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