AKR1C1 promotes non-small cell lung cancer proliferation via crosstalk between HIF-1α and metabolic reprogramming
Non-small cell lung cancer (NSCLC) ranks first among cancer death worldwide. Despite efficacy and safety priority, targeted therapy only benefits ∼30% patients, leading to the unchanged survival rates for whole NSCLC patients. Metabolic reprogramming occurs to offer energy and intermediates for fuel...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Neoplasia Press, Inc.
2022
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |