AKR1C1 promotes non-small cell lung cancer proliferation via crosstalk between HIF-1α and metabolic reprogramming
Non-small cell lung cancer (NSCLC) ranks first among cancer death worldwide. Despite efficacy and safety priority, targeted therapy only benefits ∼30% patients, leading to the unchanged survival rates for whole NSCLC patients. Metabolic reprogramming occurs to offer energy and intermediates for fuel...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Neoplasia Press, Inc.
2022
|
Subjects: | |
Online Access: | View Fulltext in Publisher |