T cell-attracting CCL18 chemokine is a dominant rejection signal during limb transplantation

T cell-attracting CCL18 chemokine is a dominant rejection signal during limb transplantation

Limb transplantation is a life-changing procedure for amputees. However, limb recipients have a 6-fold greater rejection rate than solid organ transplant recipients, related in part to greater immunogenicity of the skin. Here, we report a detailed immunological and molecular characterization of indi...

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Bibliographic Details
Main Authors: Abarzua, P. (Author), Aoyama, B.T (Author), Borges, T.J (Author), Clark, R.A (Author), Gassen, R.B (Author), Gluhova, D. (Author), Islam, S.A (Author), Kollar, B. (Author), Lian, C.G (Author), Lima-Filho, M. (Author), Murphy, G.F (Author), Pomahac, B. (Author), Riella, L.V (Author), Talbot, S.G (Author)
Format: Article
Language:English
Published: Cell Press 2022
Subjects:
CCL18
CCR8
chemokines
extremity
limb transplantation
rejection
upper extremity transplantation
vascular composite allograft
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