Targeting LAG3/GAL-3 to overcome immunosuppression and enhance anti-tumor immune responses in multiple myeloma

Immune profiling in patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering multiple myeloma (SMM), and multiple myeloma (MM) provides the framework for developing novel immunotherapeutic strategies. Here, we demonstrate decreased CD4+ Th cells, increased Treg and G-type...

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Bibliographic Details
Main Authors: Accardi, F. (Author), Anderson, K.C (Author), Bae, J. (Author), Hideshima, T. (Author), Munshi, N.C (Author), Prabhala, R. (Author), Richardson, P.G (Author), Rowell, S. (Author), Shambley, A. (Author), Tai, Y.-T (Author), Wen, K. (Author)
Format: Article
Language:English
Published: Springer Nature 2022
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Online Access:View Fulltext in Publisher