A cross-species assay demonstrates that reward responsiveness is enduringly impacted by adverse, unpredictable early-life experiences
Exposure to early-life adversity (ELA) is associated with several neuropsychiatric conditions, including major depressive disorder, yet causality is difficult to establish in humans. Recent work in rodents has implicated impaired reward circuit signaling in anhedonic-like behavior after ELA exposure...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |