TMEM189 negatively regulates the stability of ULK1 protein and cell autophagy
ULK1 is crucial for initiating autophagosome formation and its activity is tightly regulated by post-translational modifications and protein-protein interactions. In the present study, we demonstrate that TMEM189 (Transmembrane protein 189), also known as plasmanylethanolamine desaturase 1 (PEDS1),...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2022
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Online Access: | View Fulltext in Publisher |