CPT1A-mediated fatty acid oxidation promotes cell proliferation via nucleoside metabolism in nasopharyngeal carcinoma

CPT1A-mediated fatty acid oxidation promotes cell proliferation via nucleoside metabolism in nasopharyngeal carcinoma

As the first rate-limiting enzyme in fatty acid oxidation (FAO), CPT1 plays a significant role in metabolic adaptation in cancer pathogenesis. FAO provides an alternative energy supply for cancer cells and is required for cancer cell survival. Given the high proliferation rate of cancer cells, nucle...

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Bibliographic Details
Main Authors: Bode, A.M (Author), Cao, Y. (Author), Dong, X. (Author), Du, Q. (Author), Fan, J. (Author), Gao, Q. (Author), Hu, J. (Author), Li, W. (Author), Li, Y. (Author), Liao, W. (Author), Liu, N. (Author), Luo, X. (Author), Shi, F. (Author), Tan, Z. (Author), Tang, M. (Author), Weng, X. (Author), Wu, W. (Author), Xiao, L. (Author), Xie, L. (Author), Yang, L. (Author), Zhang, X. (Author), Zhao, L. (Author), Zhou, J. (Author)
Format: Article
Language:English
Published: Springer Nature 2022
Subjects:
animal
Animals
Carnitine O-Palmitoyltransferase
carnitine palmitoyltransferase
cell proliferation
Cell Proliferation
fatty acid
Fatty Acids
genetics
lipid metabolism
Lipid Metabolism
metabolism
Mice
Mice, Nude
mouse
Nasopharyngeal Carcinoma
Nasopharyngeal Neoplasms
nasopharynx carcinoma
nasopharynx tumor
nucleoside
Nucleosides
nucleotide
Nucleotides
nude mouse
oxidation reduction reaction
Oxidation-Reduction
physiology
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